Tm9sf2 | transmembrane 9 superfamily member 2

GeneMGI:1915309Synonyms: D14Ertd64e, 1500001N15Rik, +1 more

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Immune system Embryo Growth/size/body region Hematopoietic system Mortality/aging

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased mean corpuscular hemoglobin concentration1 supporting datasetTm9sf2em1(IMPC)TcpheterozygoteEarly adult3.36x10-5 
embryonic lethality prior to tooth bud stage1 supporting datasetTm9sf2em1(IMPC)TcphomozygoteE12.5N/A * 
abnormal embryo size1 supporting datasetTm9sf2em1(IMPC)TcphomozygoteE9.5N/A * 
enlarged lymph nodes1 supporting datasetTm9sf2em1(IMPC)TcpheterozygoteEarly adultN/A * 
embryonic growth retardation1 supporting datasetTm9sf2em1(IMPC)TcphomozygoteE9.5N/A * 
preweaning lethality, complete penetrance3 supporting datasetsTm9sf2em1(IMPC)TcphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Tm9sf2em1(IMPC)TcpExon Deletionmouse
Tm9sf2tm119190(L1L2_Pgk_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Tm9sf2tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Tm9sf2tm2a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Tm9sf2tm2e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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