Nutf2 | nuclear transport factor 2

GeneMGI:1915301Synonyms: 2700067I02Rik, Ntf2, +1 more

Physiological systems

15 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Vision/eye Mortality/aging Cardiovascular system

12 No significant impact

9 Not tested

Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:70Adult tissues
0Embryo tissues

Phenotypes

cataract1 supporting datasetNutf2tm1b(KOMP)MbpheterozygoteEarly adult8.95x10-13 
decreased heart rate1 supporting datasetNutf2tm1b(KOMP)MbpheterozygoteEarly adult2.86x10-6 
abnormal lens morphology1 supporting datasetNutf2tm1b(KOMP)MbpheterozygoteEarly adult2.18x10-14 
preweaning lethality, complete penetrance1 supporting datasetNutf2tm1b(KOMP)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Nutf2tm1a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Nutf2tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Nutf2tm1b(KOMP)MbpReporter-tagged deletion allele (with selection cassette)mouse
Nutf2tm1e(KOMP)MbpTargeted, non-conditional alleleES Cell
Nutf2tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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