Zfp593 | zinc finger protein 593

GeneMGI:1915290Synonyms: E130106C14Rik, 3110024A21Rik

Physiological systems

17 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Adipose tissue Growth/size/body region Hematopoietic system Skeleton Cardiovascular system

10 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased bone mineral density1 supporting datasetZfp593em1(IMPC)JhomozygoteEarly adult1.51x10-5 
increased total body fat amount2 supporting datasetsZfp593em1(IMPC)JhomozygoteEarly adult1.38x10-5 
decreased heart rate1 supporting datasetZfp593em1(IMPC)JhomozygoteEarly adult7.64x10-5 
decreased lean body mass2 supporting datasetsZfp593em1(IMPC)JhomozygoteEarly adult1.94x10-6 
decreased heart weight1 supporting datasetZfp593em1(IMPC)JhomozygoteEarly adult4.83x10-5 
increased circulating phosphate level1 supporting datasetZfp593em1(IMPC)JhomozygoteEarly adult1.26x10-5 
decreased leukocyte cell number1 supporting datasetZfp593em1(IMPC)JhomozygoteEarly adult6.14x10-5 
decreased bone mineral content1 supporting datasetZfp593em1(IMPC)JhomozygoteEarly adult2.36x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Zfp593em1(IMPC)JIntra-exon deletionmouse

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