Cox19 | cytochrome c oxidase assembly protein 19

GeneMGI:1915283Synonyms: 1810074D02Rik, 2810437L13Rik

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Mortality/aging

16 No significant impact

5 Not tested

Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
29Embryo tissues

Phenotypes

enlarged lymph nodes1 supporting datasetCox19tm1b(EUCOMM)HmguheterozygoteEarly adultN/A * 
preweaning lethality, complete penetrance3 supporting datasetsCox19tm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
decreased circulating creatinine level1 supporting datasetCox19tm1b(EUCOMM)HmguheterozygoteEarly adult2.28x10-5 
embryonic lethality prior to tooth bud stage1 supporting datasetCox19tm1b(EUCOMM)HmguhomozygoteE12.5N/A * 
increased circulating phosphate level1 supporting datasetCox19tm1b(EUCOMM)HmguheterozygoteEarly adult7.02x10-8 
embryonic lethality prior to organogenesis1 supporting datasetCox19tm1b(EUCOMM)HmguhomozygoteE9.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cox19tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Cox19tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Cox19tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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