Mrm2 | mitochondrial rRNA methyltransferase 2

GeneMGI:1915267Synonyms: Ftsj2, 2310037B18Rik

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Vision/eye Mortality/aging Cardiovascular system

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



decreased total retina thickness	1 supporting dataset	Mrm2^em1(IMPC)Bay	heterozygote	Early adult	5.85x10^-5
preweaning lethality, incomplete penetrance	2 supporting datasets	Mrm2^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
abnormal retina blood vessel morphology	1 supporting dataset	Mrm2^em1(IMPC)Bay	heterozygote	Early adult	3.76x10^-6
embryonic lethality prior to organogenesis	1 supporting dataset	Mrm2^em1(IMPC)Bay	homozygote	E9.5	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Mrm2^em1(IMPC)Bay	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mrm2.

Associated images

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Histopathology

There is no histopathology data found for Mrm2.

IMPC related publications

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External links

No external links available for Mrm2.

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*Mrm2^em1(IMPC)Bay*	Exon Deletion	‌	mouse
*Mrm2^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Mrm2^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Mrm2^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	ES Cell

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