Trap1 | TNF receptor-associated protein 1

GeneMGI:1915265Synonyms: HSP75, 2410002K23Rik

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Vision/eye Hematopoietic system

16 No significant impact

4 Not tested

Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal eye morphology1 supporting datasetTrap1em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal lymph node morphology2 supporting datasetsTrap1em1(IMPC)MbphomozygoteEarly adultN/A * 
thrombocytopenia1 supporting datasetTrap1em1(IMPC)MbphomozygoteEarly adult1.21x10-16 
decreased circulating phosphate level1 supporting datasetTrap1em1(IMPC)MbphomozygoteEarly adult3.46x10-5 
decreased circulating creatinine level1 supporting datasetTrap1em1(IMPC)MbphomozygoteEarly adult7.95x10-5 
decreased monocyte cell number1 supporting datasetTrap1em1(IMPC)MbphomozygoteEarly adult7.29x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Trap1em1(IMPC)MbpExon Deletionmouse

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