Tomm20 | translocase of outer mitochondrial membrane 20

GeneMGI:1915202Synonyms: TOM20, 1810060K07Rik

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Immune system Hematopoietic system Behavior/neurological Mortality/aging

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance1 supporting datasetTomm20em1(IMPC)JhomozygoteEarly adultN/A * 
embryonic lethality prior to organogenesis1 supporting datasetTomm20em1(IMPC)JhomozygoteE9.5N/A * 
abnormal vocalization1 supporting datasetTomm20em1(IMPC)JheterozygoteEarly adult2.42x10-10 
increased leukocyte cell number1 supporting datasetTomm20em1(IMPC)JheterozygoteEarly adult4.68x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Tomm20em1(IMPC)JExon Deletionmouse
Tomm20tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell

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