Dennd10 | DENN domain containing 10

GeneMGI:1915144Synonyms: 1810055E12Rik, Fam45a

Physiological systems

22 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Immune system Growth/size/body region Limbs/digits/tail Hematopoietic system Cardiovascular system

17 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal spleen morphology	2 supporting datasets	Dennd10^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged heart	1 supporting dataset	Dennd10^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal digit morphology	1 supporting dataset	Dennd10^{em1(IMPC)Ccpcz}	homozygote	Early adult	4.99x10^-8
enlarged spleen	1 supporting dataset	Dennd10^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal heart morphology	1 supporting dataset	Dennd10^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dennd10.

Associated images

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Histopathology

There is no histopathology data found for Dennd10.

IMPC related publications

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External links

No external links available for Dennd10.

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*Dennd10^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Dennd10^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Dennd10^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Dennd10^{tm46173(L1L2_gt1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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