Cdca5 | cell division cycle associated 5
Physiological systems
19 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Hearing/vestibular/ear Vision/eye Mortality/aging
15 No significant impact
5 Not tested
Data collections
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
21Embryo tissues
| increased circulating chloride level | 1 supporting dataset | Cdca5tm1.1(KOMP)Vlcg | heterozygote | Early adult | 4.3x10-10 | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Cdca5tm1.1(KOMP)Vlcg | homozygote | E12.5 | N/A * | ||
| abnormal auditory brainstem response | 2 supporting datasets | Cdca5tm1.1(KOMP)Vlcg | heterozygote | Early adult | 2.26x10-5 | ||
| increased circulating alanine transaminase level | 1 supporting dataset | Cdca5tm1.1(KOMP)Vlcg | heterozygote | Early adult | 3.2x10-9 | ||
| increased circulating sodium level | 1 supporting dataset | Cdca5tm1.1(KOMP)Vlcg | heterozygote | Early adult | 2.53x10-6 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Cdca5tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Cdca5tm1.1(KOMP)Vlcg | homozygote | E9.5 | N/A * | ||
| abnormal lens morphology | 1 supporting dataset | Cdca5tm1.1(KOMP)Vlcg | heterozygote | Early adult | 1.16x10-5 |
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External links
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| Cdca5tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Cdca5tm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Cdca5tm47150(L1L2_gt0) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |