Rab32 | RAB32, member RAS oncogene family

GeneMGI:1915094Synonyms: 2810011A17Rik

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Reproductive system Growth/size/body region Behavior/neurological Cardiovascular system Mortality/aging Renal/urinary system

15 No significant impact

3 Not tested

Gene metrics:6Significant phenotypes
1Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

increased kidney weight1 supporting datasetRab32tm1b(KOMP)WtsihomozygoteEarly adult1.36x10-5 
enlarged heart1 supporting datasetRab32tm1b(KOMP)WtsihomozygoteEarly adultN/A * 
preweaning lethality, incomplete penetrance3 supporting datasetsRab32tm1b(KOMP)WtsihomozygoteEarly adultN/A * 
increased grip strength1 supporting datasetRab32tm1b(KOMP)WtsiheterozygoteEarly adult7.71x10-5 
abnormal heart morphology1 supporting datasetRab32tm1b(KOMP)WtsihomozygoteEarly adultN/A * 
hydrometra1 supporting datasetRab32tm1b(KOMP)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Rab32tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Rab32tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Rab32tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Rab32tm2a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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