Gpsm1 | G-protein signalling modulator 1 (AGS3-like, C. elegans)

GeneMGI:1915089Synonyms: 1810037C22Rik, Ags3

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Integument Growth/size/body region Respiratory system Renal/urinary system

16 No significant impact

3 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

decreased bronchoconstrictive response1 supporting datasetGpsm1tm2b(KOMP)WtsihomozygoteEarly adult1.54x10-5 
decreased body length1 supporting datasetGpsm1tm2b(KOMP)WtsihomozygoteEarly adult6.68x10-10 
decreased pulmonary ventilation2 supporting datasetsGpsm1tm2b(KOMP)WtsihomozygoteEarly adult2.51x10-10 
abnormal skin morphology1 supporting datasetGpsm1tm2b(KOMP)WtsihomozygoteEarly adultN/A * 
abnormal kidney morphology1 supporting datasetGpsm1tm2b(KOMP)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Gpsm1tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Gpsm1tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Gpsm1tm2a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Gpsm1tm2b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Gpsm1tm2e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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