Tiprl | TIP41, TOR signalling pathway regulator-like (S. cerevisiae)
Physiological systems
19 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Embryo Growth/size/body region Nervous system Behavior/neurological Mortality/aging
14 No significant impact
5 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
50Embryo tissues
| preweaning lethality, complete penetrance | 1 supporting dataset | Tiprltm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| abnormal forebrain development | 1 supporting dataset | Tiprltm1.1(KOMP)Vlcg | homozygote | E9.5 | N/A * | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Tiprltm1.1(KOMP)Vlcg | homozygote | E12.5 | N/A * | ||
| decreased thigmotaxis | 2 supporting datasets | Tiprltm1.1(KOMP)Vlcg | heterozygote | Early adult | 3.54x10-5 | ||
| embryonic growth retardation | 1 supporting dataset | Tiprltm1.1(KOMP)Vlcg | homozygote | E9.5 | N/A * | ||
| abnormal startle reflex | 1 supporting dataset | Tiprltm1.1(KOMP)Vlcg | heterozygote | Early adult | 1.33x10-5 |
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External links
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| Tiprltm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Tiprltm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Tiprltm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |