Rer1 | retention in endoplasmic reticulum sorting receptor 1

GeneMGI:1915080Synonyms: 5830454N22Rik, 1110060F11Rik

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Behavior/neurological Skeleton Mortality/aging

14 No significant impact

7 Not tested

Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
25Embryo tissues

Phenotypes

decreased thigmotaxis6 supporting datasetsRer1tm1.1(KOMP)VlcgheterozygoteEarly adult4.44x10-6 
abnormal behavior1 supporting datasetRer1tm1.1(KOMP)VlcgheterozygoteEarly adult2.43x10-5 
embryonic lethality prior to organogenesis1 supporting datasetRer1tm1.1(KOMP)VlcghomozygoteE9.5N/A * 
abnormal bone structure1 supporting datasetRer1tm1.1(KOMP)VlcgheterozygoteEarly adult3.67x10-7 
decreased bone mineral content1 supporting datasetRer1tm1.1(KOMP)VlcgheterozygoteEarly adult7.28x10-5 
hyperactivity2 supporting datasetsRer1tm1.1(KOMP)VlcgheterozygoteEarly adult2.66x10-13 
preweaning lethality, complete penetrance1 supporting datasetRer1tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Rer1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Rer1tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Rer1tm373379(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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