Tmem70 | transmembrane protein 70
Physiological systems
20 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Embryo Growth/size/body region Nervous system Mortality/aging Craniofacial
15 No significant impact
4 Not tested
Data collections
Gene metrics:9Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
abnormal embryo turning | 1 supporting dataset | Tmem70em2(IMPC)Bay | homozygote | E9.5 | N/A * | ||
abnormal neural tube morphology | 1 supporting dataset | Tmem70em2(IMPC)Bay | homozygote | E9.5 | N/A * | ||
abnormal somite shape | 1 supporting dataset | Tmem70em2(IMPC)Bay | homozygote | E9.5 | N/A * | ||
abnormal embryo turning | 1 supporting dataset | Tmem70em2(IMPC)Bay | heterozygote | E9.5 | N/A * | ||
abnormal embryo size | 1 supporting dataset | Tmem70em2(IMPC)Bay | homozygote | E9.5 | N/A * | ||
embryonic growth retardation | 1 supporting dataset | Tmem70em2(IMPC)Bay | heterozygote | E9.5 | N/A * | ||
abnormal embryo size | 1 supporting dataset | Tmem70em2(IMPC)Bay | heterozygote | E9.5 | N/A * | ||
abnormal embryo development | 1 supporting dataset | Tmem70em2(IMPC)Bay | homozygote | E9.5 | N/A * | ||
abnormal pharyngeal arch morphology | 1 supporting dataset | Tmem70em2(IMPC)Bay | homozygote | E9.5 | N/A * | ||
preweaning lethality, complete penetrance | 3 supporting datasets | Tmem70em2(IMPC)Bay | homozygote | Early adult | N/A * |
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External links
No external links available for Tmem70.
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Tmem70em1(IMPC)Bay | | mouse | |
Tmem70em2(IMPC)Bay | Exon Deletion | | mouse |
Tmem70tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
Tmem70tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |