Pllp | plasma membrane proteolipid

GeneMGI:1915051Synonyms: Tm4sf11, 0610010I06Rik, +1 more

Physiological systems

20 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Endocrine/exocrine gland Integument Vision/eye Behavior/neurological Renal/urinary system

13 No significant impact

4 Not tested

Gene metrics:10Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal kidney morphology2 supporting datasetsPllptm1(KOMP)VlcghomozygoteEarly adultN/A * 
abnormal vitreous body morphology1 supporting datasetPllptm1(KOMP)VlcghomozygoteEarly adult5.99x10-5 
small kidney2 supporting datasetsPllptm1(KOMP)VlcghomozygoteEarly adultN/A * 
enlarged testis1 supporting datasetPllptm1(KOMP)VlcghomozygoteEarly adultN/A * 
decreased locomotor activity2 supporting datasetsPllptm1(KOMP)VlcghomozygoteEarly adult3.78x10-5 
abnormal testis morphology1 supporting datasetPllptm1(KOMP)VlcghomozygoteEarly adultN/A * 
increased circulating serum albumin level1 supporting datasetPllptm1(KOMP)VlcghomozygoteEarly adult1.9x10-5 
abnormal skin morphology1 supporting datasetPllptm1(KOMP)VlcghomozygoteEarly adultN/A * 
increased circulating cholesterol level1 supporting datasetPllptm1(KOMP)VlcghomozygoteEarly adult4.67x10-6 
cataract1 supporting datasetPllptm1(KOMP)VlcghomozygoteEarly adult6.35x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Pllptm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
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