Rab39b | RAB39B, member RAS oncogene family

GeneMGI:1915040Synonyms: 6330580M05Rik

Physiological systems

21 / 24 physiological systems tested

13 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Integument Endocrine/exocrine gland Growth/size/body region Digestive/alimentary Hearing/vestibular/ear Liver/biliary system Hematopoietic system Behavior/neurological Cardiovascular system Renal/urinary system

8 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:20Significant phenotypes

4Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



small ovary	1 supporting dataset	Rab39b^em1(IMPC)Tcp	homozygote	Late adult	N/A ^*
decreased spleen weight	1 supporting dataset	Rab39b^em1(IMPC)Tcp	hemizygote	Late adult	1.47x10^-5
tremors	1 supporting dataset	Rab39b^em1(IMPC)Tcp	homozygote	Late adult	9.23x10^-7
hydrometra	1 supporting dataset	Rab39b^em1(IMPC)Tcp	homozygote	Late adult	N/A ^*
enlarged urinary bladder	1 supporting dataset	Rab39b^em1(IMPC)Tcp	hemizygote	Late adult	N/A ^*
increased circulating aspartate transaminase level	1 supporting dataset	Rab39b^em1(IMPC)Tcp	homozygote	Early adult	6.99x10^-5
abnormal liver morphology	1 supporting dataset	Rab39b^em1(IMPC)Tcp	homozygote	Late adult	N/A ^*
decreased heart weight	1 supporting dataset	Rab39b^em1(IMPC)Tcp	hemizygote	Late adult	2.17x10^-5
decreased fasting circulating glucose level	1 supporting dataset	Rab39b^em1(IMPC)Tcp	homozygote	Late adult	9.3x10^-5
abnormal freezing behavior	1 supporting dataset	Rab39b^em1(IMPC)Tcp	homozygote	Early adult	1.88x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rab39b.

Associated images

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Histopathology

There is no histopathology data found for Rab39b.

IMPC related publications

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External links

No external links available for Rab39b.

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*Rab39b^em1(IMPC)Tcp*	Intra-exon deletion	‌	mouse
*Rab39b^em2(IMPC)Tcp*	Intra-exon deletion	‌	mouse
*Rab39b^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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