Nudt13 | nudix hydrolase 13

GeneMGI:1914975Synonyms: nudix (nucleoside diphosphate linked moiety X)-type motif 13, 4933433B15Rik

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Vision/eye Cardiovascular system

15 No significant impact

6 Not tested

Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:51Adult tissues
0Embryo tissues

Phenotypes

abnormal retina blood vessel morphology1 supporting datasetNudt13tm2b(EUCOMM)HmguhomozygoteEarly adult3.33x10-5 
increased fasting circulating glucose level1 supporting datasetNudt13tm2b(EUCOMM)HmguhomozygoteEarly adult4.4x10-5 
decreased total retina thickness1 supporting datasetNudt13tm2b(EUCOMM)HmguhomozygoteEarly adult7.66x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Nudt13tm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Nudt13tm2b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Nudt13tm2e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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