Aldh3b1 | aldehyde dehydrogenase 3 family, member B1

GeneMGI:1914939Synonyms: ALDH7, ALDH4, +1 more

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Growth/size/body region Skeleton Mortality/aging

15 No significant impact

6 Not tested

Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

decreased bone mineral density1 supporting datasetAldh3b1tm1b(EUCOMM)WtsihomozygoteEarly adult1.15x10-5 
preweaning lethality, incomplete penetrance1 supporting datasetAldh3b1tm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
decreased lean body mass1 supporting datasetAldh3b1tm1b(EUCOMM)WtsihomozygoteEarly adult3.01x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Aldh3b1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Aldh3b1tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Aldh3b1tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Aldh3b1tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Aldh3b1tm2e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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