Dnaaf4 | dynein axonemal assembly factor 4

GeneMGI:1914935Synonyms: 1700010I24Rik, Dyx1c1, +2 more

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Vision/eye Behavior/neurological Mortality/aging

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

3Associated diseases

Expression examined in:48Adult tissues

50Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, incomplete penetrance	1 supporting dataset	Dnaaf4^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
impaired pupillary reflex	1 supporting dataset	Dnaaf4^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.28x10^-8
hyperactivity	1 supporting dataset	Dnaaf4^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	4.55x10^-5
trunk curl	1 supporting dataset	Dnaaf4^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	4.69x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dnaaf4.

Associated images

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Histopathology

There is no histopathology data found for Dnaaf4.

IMPC related publications

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External links

No external links available for Dnaaf4.

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*Dnaaf4^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Dnaaf4^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Dnaaf4^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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