Mrpl18 | mitochondrial ribosomal protein L18

GeneMGI:1914931Synonyms: HSPC071, 1010001C05Rik, +1 more

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Vision/eye Mortality/aging

17 No significant impact

5 Not tested

Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
25Embryo tissues

Phenotypes

embryonic lethality prior to tooth bud stage1 supporting datasetMrpl18tm1.1(KOMP)VlcghomozygoteE12.5N/A * 
preweaning lethality, complete penetrance1 supporting datasetMrpl18tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
persistence of hyaloid vascular system1 supporting datasetMrpl18tm1.1(KOMP)VlcgheterozygoteEarly adult2.24x10-5 
cataract1 supporting datasetMrpl18tm1.1(KOMP)VlcgheterozygoteEarly adult5.74x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Mrpl18tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Mrpl18tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Mrpl18tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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