Sdhb | succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
Physiological systems
19 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Hematopoietic system Behavior/neurological Mortality/aging Renal/urinary system
13 No significant impact
5 Not tested
Data collections
Gene metrics:6Significant phenotypes
10Associated diseases
Expression examined in:70Adult tissues
0Embryo tissues
| abnormal kidney morphology | 1 supporting dataset | Sdhbtm1b(EUCOMM)Hmgu | heterozygote | Early adult | N/A * | ||
| increased fasting circulating glucose level | 1 supporting dataset | Sdhbtm1b(EUCOMM)Hmgu | heterozygote | Early adult | 7.25x10-5 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Sdhbtm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| decreased mean corpuscular hemoglobin concentration | 1 supporting dataset | Sdhbtm1b(EUCOMM)Hmgu | heterozygote | Early adult | 5.09x10-5 | ||
| decreased locomotor activity | 1 supporting dataset | Sdhbtm1b(EUCOMM)Hmgu | heterozygote | Early adult | 8.27x10-5 | ||
| decreased neutrophil cell number | 1 supporting dataset | Sdhbtm1b(EUCOMM)Hmgu | heterozygote | Early adult | 5.21x10-5 |
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External links
No external links available for Sdhb.
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| Sdhbtm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Sdhbtm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Sdhbtm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | es cell |