Slc39a8 | solute carrier family 39 (metal ion transporter), member 8

GeneMGI:1914797Synonyms: ZIP8, BIGM103, +1 more

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye Mortality/aging

17 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

2Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal retina morphology	1 supporting dataset	Slc39a8^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	2.1x10^-6
preweaning lethality, complete penetrance	1 supporting dataset	Slc39a8^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
increased circulating triglyceride level	1 supporting dataset	Slc39a8^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	2.38x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Slc39a8.

Associated images

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Histopathology

There is no histopathology data found for Slc39a8.

IMPC related publications

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External links

No external links available for Slc39a8.

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*Slc39a8^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Slc39a8^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Slc39a8^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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