Dock6 | dedicator of cytokinesis 6

GeneMGI:1914789Synonyms: C330023D02Rik, 2410095B20Rik, +1 more

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Hematopoietic system Mortality/aging

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, incomplete penetrance	1 supporting dataset	Dock6^em1(IMPC)J	homozygote	Early adult	N/A ^*
increased erythrocyte cell number	1 supporting dataset	Dock6^em1(IMPC)J	heterozygote	Early adult	3.66x10^-5
increased circulating bilirubin level	1 supporting dataset	Dock6^em1(IMPC)J	heterozygote	Early adult	9.08x10^-9
increased hemoglobin content	1 supporting dataset	Dock6^em1(IMPC)J	heterozygote	Early adult	6.2x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dock6.

Associated images

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Histopathology

There is no histopathology data found for Dock6.

IMPC related publications

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External links

No external links available for Dock6.

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*Dock6^em1(IMPC)J*	Indel	‌	mouse
*Dock6^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Dock6^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Dock6^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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