Agpat2 | 1-acylglycerol-3-phosphate O-acyltransferase 2

GeneMGI:1914762Synonyms: 2510002J07Rik, BSCL1, +1 more

Physiological systems

24 / 24 physiological systems tested

12 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Digestive/alimentary Liver/biliary system Hematopoietic system Behavior/neurological Skeleton Mortality/aging Renal/urinary system

12 No significant impact

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:17Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



enlarged uterus	1 supporting dataset	Agpat2^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Agpat2^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged kidney	1 supporting dataset	Agpat2^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
enlarged liver	1 supporting dataset	Agpat2^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
enlarged spleen	1 supporting dataset	Agpat2^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
abnormal liver morphology	1 supporting dataset	Agpat2^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
increased circulating total protein level	1 supporting dataset	Agpat2^{em1(IMPC)Ccpcz}	heterozygote	Early adult	5.27x10^-7
no spontaneous movement	1 supporting dataset	Agpat2^{em1(IMPC)Ccpcz}	homozygote	E18.5	N/A ^*
abnormal stomach morphology	1 supporting dataset	Agpat2^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
increased circulating serum albumin level	1 supporting dataset	Agpat2^{em1(IMPC)Ccpcz}	heterozygote	Early adult	3.16x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Agpat2.

Associated images

Loading...

Histopathology

There is no histopathology data found for Agpat2.

IMPC related publications

Loading...

External links

No external links available for Agpat2.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Agpat2^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Agpat2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Agpat2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

My Genes