Calcoco1 | calcium binding and coiled coil domain 1

GeneMGI:1914738Synonyms: 1810009B06Rik, CoCoA, +1 more

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Vision/eye Behavior/neurological Skeleton Renal/urinary system

14 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



decreased circulating total protein level	1 supporting dataset	Calcoco1^em1(IMPC)H	homozygote	Early adult	2.59x10^-6
abnormal startle reflex	1 supporting dataset	Calcoco1^em1(IMPC)H	homozygote	Late adult	5.61x10^-6
decreased circulating phosphate level	1 supporting dataset	Calcoco1^em1(IMPC)H	homozygote	Early adult	6.46x10^-5
abnormal retina morphology	1 supporting dataset	Calcoco1^em1(IMPC)H	homozygote	Late adult	6.33x10^-22
increased bone mineral density	1 supporting dataset	Calcoco1^em1(IMPC)H	homozygote	Late adult	4.85x10^-8
enlarged urinary bladder	1 supporting dataset	Calcoco1^em1(IMPC)H	homozygote	Late adult	N/A ^*
enlarged kidney	1 supporting dataset	Calcoco1^em1(IMPC)H	homozygote	Late adult	N/A ^*
abnormal locomotor behavior	1 supporting dataset	Calcoco1^em1(IMPC)H	homozygote	Early adult	5.64x10^-5
cataract	1 supporting dataset	Calcoco1^em1(IMPC)H	homozygote	Late adult	4.05x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Calcoco1.

Associated images

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Histopathology

There is no histopathology data found for Calcoco1.

IMPC related publications

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External links

No external links available for Calcoco1.

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*Calcoco1^em1(IMPC)H*	Exon Deletion	‌	mouse
*Calcoco1^em2(IMPC)H*	Exon Deletion	‌	mouse
*Calcoco1^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Calcoco1^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	ES Cell
*Calcoco1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Calcoco1^{tm2a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Calcoco1^{tm2e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	ES Cell

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