Poc5 | POC5 centriolar protein

GeneMGI:1914713Synonyms: 1200014M14Rik

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Reproductive system Endocrine/exocrine gland Nervous system Behavior/neurological Mortality/aging

13 No significant impact

6 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal ovary morphology1 supporting datasetPoc5em1(IMPC)TcphomozygoteEarly adultN/A * 
preweaning lethality, incomplete penetrance1 supporting datasetPoc5em1(IMPC)TcphomozygoteEarly adultN/A * 
decreased exploration in new environment1 supporting datasetPoc5em1(IMPC)TcphomozygoteEarly adult2.25x10-9 
decreased prepulse inhibition2 supporting datasetsPoc5em1(IMPC)TcphomozygoteEarly adult6.18x10-5 
small testis1 supporting datasetPoc5em1(IMPC)TcphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Poc5em1(IMPC)TcpExon Deletionmouse
Poc5tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Poc5tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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