Rfk | riboflavin kinase

GeneMGI:1914688Synonyms: flavokinase, ATP:riboflavin 5'-phosphotransferase, +1 more

Physiological systems

21 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Vision/eye Hematopoietic system Mortality/aging Renal/urinary system

14 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal kidney morphology	2 supporting datasets	Rfk^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
persistence of hyaloid vascular system	1 supporting dataset	Rfk^em1(IMPC)Mbp	heterozygote	Early adult	1.14x10^-9
single kidney	1 supporting dataset	Rfk^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
abnormal testis morphology	1 supporting dataset	Rfk^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Rfk^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
small kidney	2 supporting datasets	Rfk^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
enlarged testis	1 supporting dataset	Rfk^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
embryonic lethality prior to organogenesis	1 supporting dataset	Rfk^em1(IMPC)Mbp	homozygote	E9.5	N/A ^*
small spleen	1 supporting dataset	Rfk^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Rfk^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rfk.

Associated images

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Histopathology

There is no histopathology data found for Rfk.

IMPC related publications

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External links

No external links available for Rfk.

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*Rfk^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Rfk^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Rfk^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Rfk^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Rfk^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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