Pdlim7 | PDZ and LIM domain 7

GeneMGI:1914649Synonyms: 1110003B01Rik, Enigma, +1 more

Physiological systems

20 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Immune system Integument Growth/size/body region Vision/eye Liver/biliary system Hematopoietic system Cardiovascular system

13 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal vitreous body morphology	1 supporting dataset	Pdlim7^em1(IMPC)Mbp	homozygote	Early adult	5.99x10^-5
abnormal skin morphology	1 supporting dataset	Pdlim7^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
enlarged heart	1 supporting dataset	Pdlim7^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
cataract	1 supporting dataset	Pdlim7^em1(IMPC)Mbp	homozygote	Early adult	6.35x10^-5
abnormal lymph node morphology	1 supporting dataset	Pdlim7^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
enlarged spleen	1 supporting dataset	Pdlim7^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal liver morphology	1 supporting dataset	Pdlim7^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
enlarged lymph nodes	1 supporting dataset	Pdlim7^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
increased mean platelet volume	1 supporting dataset	Pdlim7^em1(IMPC)Mbp	homozygote	Early adult	4.91x10^-6
abnormal spleen morphology	1 supporting dataset	Pdlim7^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pdlim7.

Associated images

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Histopathology

There is no histopathology data found for Pdlim7.

IMPC related publications

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External links

No external links available for Pdlim7.

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*Pdlim7^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Pdlim7^{tm373584(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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