Prss3b | serine protease 3B

GeneMGI:1914623Synonyms: 2210010C04Rik, cationic trypsinogen (isoform T7), +1 more

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Nervous system Vision/eye Behavior/neurological Cardiovascular system

13 No significant impact

6 Not tested

Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
0Embryo tissues

Phenotypes

hyperactivity3 supporting datasetsPrss3btm1b(KOMP)WtsihomozygoteEarly adult3.92x10-6 
decreased prepulse inhibition4 supporting datasetsPrss3btm1b(KOMP)WtsihomozygoteEarly adult8.21x10-8 
abnormal retina vasculature morphology1 supporting datasetPrss3btm1b(KOMP)WtsihomozygoteEarly adult3.81x10-5 
decreased circulating alanine transaminase level1 supporting datasetPrss3btm1b(KOMP)WtsihomozygoteEarly adult1.01x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* This parameter was manually assessed for significance.
Download data as:  

lacZ Expression

Associated images

Loading...

Histopathology

IMPC related publications

Loading...

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

Prss3btm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Prss3btm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Prss3btm45180(L1L2_st2)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter