Dipk1a | divergent protein kinase domain 1A

GeneMGI:1914516Synonyms: 2900024C23Rik, Fam69a

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue Growth/size/body region Cardiovascular system

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased heart weight	1 supporting dataset	Dipk1a^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	2.84x10^-8
decreased total body fat amount	1 supporting dataset	Dipk1a^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	2.27x10^-5
increased circulating sodium level	1 supporting dataset	Dipk1a^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.03x10^-7
increased lean body mass	2 supporting datasets	Dipk1a^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	2.29x10^-6
increased circulating alkaline phosphatase level	1 supporting dataset	Dipk1a^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	6.44x10^-11

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dipk1a.

Associated images

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Histopathology

There is no histopathology data found for Dipk1a.

IMPC related publications

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External links

No external links available for Dipk1a.

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*Dipk1a^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse

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