Peli1 | pellino 1

GeneMGI:1914495Synonyms: A930031K15Rik, D11Ertd676e, +1 more

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Growth/size/body region Nervous system Hematopoietic system Cardiovascular system

15 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



enlarged heart	1 supporting dataset	Peli1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
improved glucose tolerance	1 supporting dataset	Peli1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.15x10^-6
decreased body length	1 supporting dataset	Peli1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.26x10^-5
abnormal spleen morphology	1 supporting dataset	Peli1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
enlarged spleen	1 supporting dataset	Peli1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
increased lean body mass	1 supporting dataset	Peli1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	9.8x10^-5
increased neutrophil cell number	1 supporting dataset	Peli1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	8.32x10^-5
increased spleen weight	1 supporting dataset	Peli1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.52x10^-13
decreased brain weight	1 supporting dataset	Peli1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.83x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Peli1.

Associated images

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Histopathology

There is no histopathology data found for Peli1.

IMPC related publications

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External links

No external links available for Peli1.

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*Peli1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Peli1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Peli1^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Peli1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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