Prpf18 | pre-mRNA processing factor 18

GeneMGI:1914479Synonyms: 2810441A10Rik

Physiological systems

22 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Mortality/aging

21 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

41Embryo tissues

Phenotypes

Life Stage:



preweaning lethality, complete penetrance	3 supporting datasets	Prpf18^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
embryonic lethality prior to organogenesis	1 supporting dataset	Prpf18^{tm1.1(KOMP)Vlcg}	homozygote	E9.5	N/A ^*
embryonic lethality prior to tooth bud stage	1 supporting dataset	Prpf18^{tm1.1(KOMP)Vlcg}	homozygote	E12.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Prpf18.

Associated images

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Histopathology

There is no histopathology data found for Prpf18.

IMPC related publications

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External links

No external links available for Prpf18.

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*Prpf18^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Prpf18^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Prpf18^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Prpf18^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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