Pfdn1 | prefoldin 1
Physiological systems
19 / 24 physiological systems tested
8 Significantly impacted by the knock-out
Embryo Growth/size/body region Digestive/alimentary Limbs/digits/tail Behavior/neurological Mortality/aging Cardiovascular system Craniofacial
11 No significant impact
5 Not tested
Data collections
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| cleft palate | 1 supporting dataset | Pfdn1em1(IMPC)J | homozygote | E18.5 | N/A * | ||
| abnormal locomotor behavior | 1 supporting dataset | Pfdn1em1(IMPC)J | heterozygote | Early adult | 1.52x10-5 | ||
| abnormal embryo size | 1 supporting dataset | Pfdn1em1(IMPC)J | homozygote | E18.5 | N/A * | ||
| hemorrhage | 1 supporting dataset | Pfdn1em1(IMPC)J | homozygote | E18.5 | N/A * | ||
| abnormal tail morphology | 1 supporting dataset | Pfdn1em1(IMPC)J | homozygote | E18.5 | N/A * | ||
| limb grasping | 1 supporting dataset | Pfdn1em1(IMPC)J | heterozygote | Early adult | 9.77x10-9 | ||
| decreased exploration in new environment | 1 supporting dataset | Pfdn1em1(IMPC)J | heterozygote | Early adult | 9.25x10-6 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Pfdn1em1(IMPC)J | homozygote | Early adult | N/A * |
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External links
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| Pfdn1em1(IMPC)J | Exon Deletion | | mouse |
| Pfdn1tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Pfdn1tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Pfdn1tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |