Lpar6 | lysophosphatidic acid receptor 6

GeneMGI:1914418Synonyms: 2610302I02Rik, P2y5, +1 more

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological

15 No significant impact

7 Not tested

Gene metrics:4Significant phenotypes
3Associated diseases
Expression examined in:49Adult tissues
50Embryo tissues

Phenotypes

decreased thigmotaxis2 supporting datasetsLpar6tm1.1(KOMP)VlcghomozygoteEarly adult9.79x10-6 
increased circulating alanine transaminase level1 supporting datasetLpar6tm1.1(KOMP)VlcghomozygoteEarly adult7.85x10-5 
hyperactivity1 supporting datasetLpar6tm1.1(KOMP)VlcghomozygoteEarly adult9.68x10-7 
abnormal behavior1 supporting datasetLpar6tm1.1(KOMP)VlcghomozygoteEarly adult9.81x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Lpar6tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Lpar6tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Lpar6tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Lpar6tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Lpar6tm2a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Lpar6tm2e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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