Sclt1 | sodium channel and clathrin linker 1

GeneMGI:1914411Synonyms: 2610207F23Rik, 4931421F20Rik

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Limbs/digits/tail Vision/eye Mortality/aging

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



polydactyly	1 supporting dataset	Sclt1^em1(IMPC)Tcp	homozygote	E18.5	N/A ^*
preweaning lethality, incomplete penetrance	3 supporting datasets	Sclt1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
increased circulating triglyceride level	1 supporting dataset	Sclt1^em1(IMPC)Tcp	heterozygote	Early adult	1.89x10^-5
abnormal eye morphology	1 supporting dataset	Sclt1^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Sclt1.

Associated images

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Histopathology

There is no histopathology data found for Sclt1.

IMPC related publications

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External links

No external links available for Sclt1.

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*Sclt1^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Sclt1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Sclt1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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