Gp2 | glycoprotein 2 zymogen granule membrane

GeneMGI:1914383Synonyms: 2310037I18Rik

Physiological systems

20 / 24 physiological systems tested

10 Significantly impacted by the knock-out

Reproductive system Immune system Integument Endocrine/exocrine gland Growth/size/body region Vision/eye Liver/biliary system Hematopoietic system Cardiovascular system Renal/urinary system

10 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:16Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



abnormal spleen morphology	2 supporting datasets	Gp2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal seminal vesicle morphology	1 supporting dataset	Gp2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
enlarged lymph nodes	2 supporting datasets	Gp2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal liver morphology	2 supporting datasets	Gp2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
small heart	1 supporting dataset	Gp2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal kidney morphology	2 supporting datasets	Gp2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal lymph node morphology	2 supporting datasets	Gp2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
enlarged spleen	2 supporting datasets	Gp2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
thrombocytopenia	1 supporting dataset	Gp2^em1(IMPC)Mbp	homozygote	Late adult	1.83x10^-6
small kidney	1 supporting dataset	Gp2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Gp2.

Associated images

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Histopathology

There is no histopathology data found for Gp2.

IMPC related publications

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External links

No external links available for Gp2.

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*Gp2^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Gp2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Gp2^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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