Cand2 | cullin associated and neddylation dissociated 2 (putative)

GeneMGI:1914338Synonyms: 2210404G23Rik, Tp120b

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue Growth/size/body region Hematopoietic system

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased total body fat amount	2 supporting datasets	Cand2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.66x10^-5
increased lean body mass	2 supporting datasets	Cand2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.69x10^-8
increased red blood cell distribution width	1 supporting dataset	Cand2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	8.25x10^-5
decreased circulating thyroxine level	1 supporting dataset	Cand2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	6.82x10^-5
decreased circulating iron level	1 supporting dataset	Cand2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	9.28x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cand2.

Associated images

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Histopathology

There is no histopathology data found for Cand2.

IMPC related publications

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External links

No external links available for Cand2.

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*Cand2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Cand2^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

My Genes