Mon2 | MON2 homolog, regulator of endosome to Golgi trafficking

GeneMGI:1914324Synonyms: SF21, 2610528O22Rik

Physiological systems

18 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Pigmentation Integument Growth/size/body region Behavior/neurological Mortality/aging Cardiovascular system

12 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal vocalization	1 supporting dataset	Mon2^em1(IMPC)J	heterozygote	Early adult	5.85x10^-8
preweaning lethality, complete penetrance	1 supporting dataset	Mon2^em1(IMPC)J	homozygote	Early adult	N/A ^*
increased heart weight	1 supporting dataset	Mon2^em1(IMPC)J	heterozygote	Early adult	1.13x10^-9
embryonic lethality prior to organogenesis	1 supporting dataset	Mon2^em1(IMPC)J	homozygote	E9.5	N/A ^*
abnormal coat/hair pigmentation	1 supporting dataset	Mon2^em1(IMPC)J	heterozygote	Early adult	3.78x10^-9

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mon2.

Associated images

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Histopathology

There is no histopathology data found for Mon2.

IMPC related publications

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External links

No external links available for Mon2.

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*Mon2^em1(IMPC)J*	Exon Deletion	‌	mouse
*Mon2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Mon2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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