Dynlrb1 | dynein light chain roadblock-type 1

GeneMGI:1914318Synonyms: 2010320M17Rik, km23-1, +3 more

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Skeleton Mortality/aging

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal bone structure1 supporting datasetDynlrb1tm1a(EUCOMM)WtsiheterozygoteEarly adult6.88x10-5 
preweaning lethality, complete penetrance1 supporting datasetDynlrb1tm1a(EUCOMM)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Dynlrb1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Dynlrb1tm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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