Paics | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase

GeneMGI:1914304Synonyms: PAIS, AIRC, +2 more

Physiological systems

22 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Embryo Growth/size/body region Mortality/aging

19 No significant impact

2 Not tested

Gene metrics:3Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance3 supporting datasetsPaicsem1(IMPC)MbphomozygoteEarly adultN/A * 
prenatal lethality prior to heart atrial septation1 supporting datasetPaicsem1(IMPC)MbphomozygoteE15.5N/A * 
embryonic growth retardation1 supporting datasetPaicsem1(IMPC)MbpheterozygoteE9.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Paicsem1(IMPC)MbpExon Deletionmouse

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