Ndc80 | NDC80 kinetochore complex component

GeneMGI:1914302Synonyms: Kntc2, 2610020P18Rik, +1 more

Physiological systems

17 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Mortality/aging

16 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

embryonic lethality prior to organogenesis1 supporting datasetNdc80em1(IMPC)JhomozygoteE9.5N/A * 
preweaning lethality, complete penetrance1 supporting datasetNdc80em1(IMPC)JhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ndc80em1(IMPC)JExon Deletionmouse
Ndc80tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Ndc80tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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