Riok2 | RIO kinase 2
Physiological systems
22 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Homeostasis/metabolism Mortality/aging
20 No significant impact
2 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
30Embryo tissues
| preweaning lethality, incomplete penetrance | 3 supporting datasets | Riok2tm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Riok2tm1b(KOMP)Wtsi | homozygote | E9.5 | N/A * | ||
| prenatal lethality prior to heart atrial septation | 1 supporting dataset | Riok2tm1b(KOMP)Wtsi | homozygote | E15.5 | N/A * | ||
| increased circulating alanine transaminase level | 1 supporting dataset | Riok2tm1b(KOMP)Wtsi | heterozygote | Early adult | 3.18x10-24 | ||
| increased circulating aspartate transaminase level | 1 supporting dataset | Riok2tm1b(KOMP)Wtsi | heterozygote | Early adult | 6.94x10-20 | ||
| increased circulating bilirubin level | 1 supporting dataset | Riok2tm1b(KOMP)Wtsi | heterozygote | Early adult | 1.32x10-6 |
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External links
No external links available for Riok2.
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| Riok2tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Riok2tm1(NCOM)Mfgc | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |
| Riok2tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Riok2tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Riok2tm1e(KOMP)Mbp | Targeted, non-conditional allele | | ES Cell |
| Riok2tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |