Tbc1d2b | TBC1 domain family, member 2B

GeneMGI:1914266Synonyms: 1810061M12Rik

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Hematopoietic system Behavior/neurological Skeleton

15 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased mean corpuscular volume	1 supporting dataset	Tbc1d2b^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	3.12x10^-5
increased bone mineral content	1 supporting dataset	Tbc1d2b^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	3.54x10^-5
tremors	1 supporting dataset	Tbc1d2b^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	8.51x10^-7
increased lean body mass	1 supporting dataset	Tbc1d2b^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	2.98x10^-5
decreased circulating serum albumin level	1 supporting dataset	Tbc1d2b^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	4.63x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tbc1d2b.

Associated images

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Histopathology

There is no histopathology data found for Tbc1d2b.

IMPC related publications

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External links

No external links available for Tbc1d2b.

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*Tbc1d2b^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse

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