Rnf187 | ring finger protein 187

GeneMGI:1914224Synonyms: 2410016F01Rik

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological Mortality/aging

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased locomotor activity9 supporting datasetsRnf187em1(IMPC)JhomozygoteEarly adult4.02x10-8 
increased startle reflex1 supporting datasetRnf187em1(IMPC)JhomozygoteEarly adult1.49x10-7 
increased blood urea nitrogen level1 supporting datasetRnf187em1(IMPC)JhomozygoteEarly adult8.48x10-5 
increased anxiety-related response1 supporting datasetRnf187em1(IMPC)JhomozygoteEarly adult1.75x10-5 
preweaning lethality, incomplete penetrance1 supporting datasetRnf187em1(IMPC)JhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Rnf187em1(IMPC)JWhole-gene deletionmouse
Rnf187tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Rnf187tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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