Ssbp2 | single-stranded DNA binding protein 2

GeneMGI:1914220Synonyms: Hspc116, 9330163K02Rik, +4 more

Physiological systems

21 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Reproductive system Adipose tissue Growth/size/body region Nervous system Vision/eye Behavior/neurological Cardiovascular system

14 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:13Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased heart weight	2 supporting datasets	Ssbp2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.56x10^-7
increased startle reflex	1 supporting dataset	Ssbp2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	8.62x10^-16
abnormal eye morphology	1 supporting dataset	Ssbp2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
decreased brain weight	1 supporting dataset	Ssbp2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.87x10^-7
impaired pupillary reflex	1 supporting dataset	Ssbp2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	4.62x10^-7
hyperactivity	4 supporting datasets	Ssbp2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.98x10^-5
decreased total body fat amount	1 supporting dataset	Ssbp2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	4.14x10^-7
increased lean body mass	1 supporting dataset	Ssbp2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.1x10^-8
decreased grip strength	1 supporting dataset	Ssbp2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.19x10^-5
enlarged epididymis	1 supporting dataset	Ssbp2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ssbp2.

Associated images

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Histopathology

There is no histopathology data found for Ssbp2.

IMPC related publications

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External links

No external links available for Ssbp2.

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*Ssbp2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Ssbp2^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Ssbp2^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Ssbp2^{tm43066(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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