Trit1 | tRNA isopentenyltransferase 1

GeneMGI:1914216Synonyms: MOD5, 2310075G14Rik

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Behavior/neurological Mortality/aging

16 No significant impact

6 Not tested

Gene metrics:3Significant phenotypes
1Associated diseases
Expression examined in:48Adult tissues
25Embryo tissues

Phenotypes

decreased grip strength1 supporting datasetTrit1tm1.1(KOMP)VlcgheterozygoteEarly adult8.34x10-5 
preweaning lethality, complete penetrance1 supporting datasetTrit1tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
embryonic lethality prior to organogenesis1 supporting datasetTrit1tm1.1(KOMP)VlcghomozygoteE9.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Trit1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Trit1tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Trit1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Trit1tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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