Golt1b | golgi transport 1B

GeneMGI:1914214Synonyms: 2310061A22Rik

Physiological systems

23 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Immune system Integument Endocrine/exocrine gland Growth/size/body region Hematopoietic system Behavior/neurological Cardiovascular system Renal/urinary system

15 No significant impact

1 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



enlarged lymph nodes	1 supporting dataset	Golt1b^{tm1b(EUCOMM)Wtsi}	homozygote	Late adult	N/A ^*
enlarged urinary bladder	1 supporting dataset	Golt1b^{tm1b(EUCOMM)Wtsi}	homozygote	Late adult	N/A ^*
enlarged thymus	1 supporting dataset	Golt1b^{tm1b(EUCOMM)Wtsi}	homozygote	Late adult	N/A ^*
abnormal mammary gland morphology	1 supporting dataset	Golt1b^{tm1b(EUCOMM)Wtsi}	homozygote	Late adult	N/A ^*
enlarged spleen	1 supporting dataset	Golt1b^{tm1b(EUCOMM)Wtsi}	homozygote	Late adult	N/A ^*
abnormal gait	1 supporting dataset	Golt1b^{tm1b(EUCOMM)Wtsi}	homozygote	Late adult	1.06x10^-5
increased grip strength	1 supporting dataset	Golt1b^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.36x10^-8
decreased cardiac output	1 supporting dataset	Golt1b^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	6.87x10^-6
prolonged RR interval	1 supporting dataset	Golt1b^{tm1b(EUCOMM)Wtsi}	homozygote	Late adult	4.98x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Golt1b.

Associated images

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Histopathology

There is no histopathology data found for Golt1b.

IMPC related publications

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External links

No external links available for Golt1b.

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*Golt1b^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Golt1b^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Golt1b^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Golt1b^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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