Chordc1 | cysteine and histidine rich domain containing 1

GeneMGI:1914167Synonyms: 1110001O09Rik, morgana, +1 more

Physiological systems

20 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Immune system Integument Embryo Nervous system Vision/eye Hematopoietic system Mortality/aging Renal/urinary system

12 No significant impact

4 Not tested

Gene metrics:11Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

cataract1 supporting datasetChordc1em1(IMPC)MbpheterozygoteEarly adult6.35x10-5 
abnormal kidney morphology2 supporting datasetsChordc1em1(IMPC)MbpheterozygoteEarly adultN/A * 
abnormal skin morphology1 supporting datasetChordc1em1(IMPC)MbpheterozygoteEarly adultN/A * 
preweaning lethality, complete penetrance3 supporting datasetsChordc1em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal vitreous body morphology1 supporting datasetChordc1em1(IMPC)MbpheterozygoteEarly adult5.99x10-5 
small kidney2 supporting datasetsChordc1em1(IMPC)MbpheterozygoteEarly adultN/A * 
abnormal retina morphology1 supporting datasetChordc1em1(IMPC)MbpheterozygoteEarly adult5.3x10-5 
increased neutrophil cell number1 supporting datasetChordc1em1(IMPC)MbpheterozygoteEarly adult1.79x10-5 
abnormal neural tube morphology1 supporting datasetChordc1em1(IMPC)MbpheterozygoteE9.5N/A * 
decreased lymphocyte cell number1 supporting datasetChordc1em1(IMPC)MbpheterozygoteEarly adult8.93x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Chordc1em1(IMPC)MbpExon Deletionmouse
Chordc1tm199137(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Chordc1tm199137(L1L2_Pgk_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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