Pccb | propionyl Coenzyme A carboxylase, beta polypeptide

GeneMGI:1914154Synonyms: 1300012P06Rik

Physiological systems

23 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Homeostasis/metabolism Embryo Growth/size/body region Nervous system Vision/eye Mortality/aging Cardiovascular system Craniofacial Renal/urinary system

14 No significant impact

1 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

2Associated diseases

Expression examined in:73Adult tissues

85Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



hemorrhage	1 supporting dataset	Pccb^{tm1.1(KOMP)Vlcg}	homozygote	E15.5	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Pccb^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
microphthalmia	1 supporting dataset	Pccb^{tm1.1(KOMP)Vlcg}	homozygote	E15.5	N/A ^*
edema	1 supporting dataset	Pccb^{tm1.1(KOMP)Vlcg}	homozygote	E15.5	N/A ^*
hemorrhage	1 supporting dataset	Pccb^{tm1.1(KOMP)Vlcg}	heterozygote	E15.5	N/A ^*
spina bifida	1 supporting dataset	Pccb^{tm1.1(KOMP)Vlcg}	heterozygote	E15.5	N/A ^*
spina bifida	1 supporting dataset	Pccb^{tm1.1(KOMP)Vlcg}	homozygote	E15.5	N/A ^*
abnormal craniofacial morphology	1 supporting dataset	Pccb^{tm1.1(KOMP)Vlcg}	homozygote	E15.5	N/A ^*
polycystic kidney	1 supporting dataset	Pccb^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	N/A ^*
abnormal kidney morphology	1 supporting dataset	Pccb^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Pccb.

Associated images

Loading...

Histopathology

There is no histopathology data found for Pccb.

IMPC related publications

Loading...

External links

No external links available for Pccb.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Pccb^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Pccb^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Pccb^{tm80475(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes