Mtap | methylthioadenosine phosphorylase

GeneMGI:1914152Synonyms: 1300019I21Rik

Physiological systems

21 / 24 physiological systems tested

10 Significantly impacted by the knock-out

Immune system Endocrine/exocrine gland Integument Embryo Growth/size/body region Vision/eye Liver/biliary system Hematopoietic system Mortality/aging Cardiovascular system

11 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:20Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



preweaning lethality, complete penetrance	3 supporting datasets	Mtap^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal chorioallantoic fusion	1 supporting dataset	Mtap^em1(IMPC)Mbp	homozygote	E9.5	N/A ^*
abnormal skin morphology	2 supporting datasets	Mtap^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
abnormal skin morphology	2 supporting datasets	Mtap^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
enlarged spleen	1 supporting dataset	Mtap^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
abnormal vitreous body morphology	1 supporting dataset	Mtap^em1(IMPC)Mbp	heterozygote	Early adult	6.21x10^-8
embryonic growth retardation	1 supporting dataset	Mtap^em1(IMPC)Mbp	homozygote	E9.5	N/A ^*
cataract	1 supporting dataset	Mtap^em1(IMPC)Mbp	heterozygote	Early adult	1.1x10^-7
abnormal vitelline vasculature morphology	1 supporting dataset	Mtap^em1(IMPC)Mbp	homozygote	E9.5	N/A ^*
enlarged thymus	1 supporting dataset	Mtap^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mtap.

Associated images

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Histopathology

There is no histopathology data found for Mtap.

IMPC related publications

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External links

No external links available for Mtap.

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*Mtap^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Mtap^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Mtap^{tm295871(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Mtap^{tm36358(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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